The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 13, 2010
Filed:
Jan. 13, 2005
Dongsheng Yao, Guangdong, CN;
Daling Liu, Guangdong, CN;
Min Guan, Guangdong, CN;
Chunfang Xie, Guangdong, CN;
Dongsheng Yao, Guangdong, CN;
Daling Liu, Guangdong, CN;
Min Guan, Guangdong, CN;
Chunfang Xie, Guangdong, CN;
Guangzhou Co-Win Bioengineering Co., Ltd., Guangzhou, Guangdong, CN;
Abstract
The present invention relates to a detoxifizyme with the activity of transforming aflatoxin and the gene encodes thereof. Firstly a novel protein is isolated and purified, named aflatoxin-detoxifizyme (ADTZ), which has the activity of transforming aflatoxin. The ADTZ gene is obtained through specific primers, and the gene is purified and sequenced. The gene encoding of ADTZ is cloned from the total RNA of. The recombinant protein is expressed and purified through various expression systems using genetic engineering methods. The said detoxifizyme has bioactivity of transforming AFB, reducing mutagenic effects of AFB. It has great potential for the manufacturing of feed or food and development of anti-tumor medicament.