The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2010
Filed:
Oct. 05, 2005
Hiroshi Tomiyama, Sakaki-machi, JP;
Masayuki Yokota, Chikuma, JP;
Kazuo Tokuzaki, Sakaki-machi, JP;
Ryoko Tomita, Chikuma, JP;
Hiroshi Tomiyama, Sakaki-machi, JP;
Masayuki Yokota, Chikuma, JP;
Kazuo Tokuzaki, Sakaki-machi, JP;
Ryoko Tomita, Chikuma, JP;
Kotobuki Pharmaceutical Co., Ltd., Nagano, JP;
Abstract
This invention related to a series of new phosphonic acid derivatives having anti-hyperphosphatemia activity. wherein: A is selected from —(CH)—, —CO—, —(CH)—CO—(CH)—, —(CH)—CS—(CH)— or a branched alkylene group, B ring and C ring are selected from a benzene ring, naphthalene ring, azulene ring or, heterocycle or fused heterocycle compound, D is —(CH)—, —(CH2)—O—(CH)—, —(CH)—S(O)—(CH)—, —CFor —(CH)—NR—(CH)— wherein a D ring is connected with the carbon atom composing the C ring, E is selected from an oxygen atom or a sulfur atom, P is a phosphine atom, R˜R, wherein Rand R, Rand Rare joined together with neighbored carbon atom to form 5˜7 membered saturated or unsaturated hydrocarbon ring, or 5˜6 membered fused heterocycle, R, Rand Rare not a hydrogen atom if the B ring is a benzene ring and may be the same or different and are substituents, Rand Rare may be the same or different and are substituents, Ris an alkyl group, n and m are 0-10 and o is 0-2.