The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2010
Filed:
Jun. 15, 2005
Fabio Benedetti, Trieste, IT;
Alessandro Tossi, Farra d'Isonzo, IT;
Federico Berti, Trieste, IT;
Pietro Campaner, Udine, IT;
Francesca Dinon, Trieste, IT;
Fabio Benedetti, Trieste, IT;
Alessandro Tossi, Farra d'Isonzo, IT;
Federico Berti, Trieste, IT;
Pietro Campaner, Udine, IT;
Francesca Dinon, Trieste, IT;
Universita' Degli Studi Di Treiste, Trieste, IT;
Abstract
New peptidomimetic inhibitors of retroviral proteases are in particular for human immunodeficiency virus (HIV) protease. These inhibitors include as the core structure a new diamiriodiol isostere of the dipeptide Phe-Pro having four stereogenic centers. The inhibitors have been shown to inhibit HIV-protease and can therefore be usefully employed as antivirals for post-exposure prophylaxis and as a therapy for viral infections by a retrovirus, in particular HIV. The syntheses processes of the isosteres and inhibitors are also described.