The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 2010
Filed:
Jul. 25, 2006
Applicant:
Noa Zerangue, Sunnyvale, CA (US);
Inventor:
Noa Zerangue, Sunnyvale, CA (US);
Assignee:
XenoPort, Inc., Santa Clara, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/557 (2006.01); G01N 33/566 (2006.01);
U.S. Cl.
CPC ...
Abstract
OCT3 is consistently expressed at high levels in brain microvessel endothelial cells. Disclosed herein are assays for determining whether a test material/molecule is a substrate for, and/or is actively transported by, the OCT3 transporter, and therefore a candidate substrate for crossing the blood brain barrier. The assays are useful in screening for therapeutic, cytotoxic or imaging compounds used in the treatment or diagnosis of neurological diseases.