The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2010
Filed:
Oct. 19, 2006
Thomas M. Lancaster, Stoneham, MA (US);
Wenyi Cai, Somerville, MA (US);
Ryan Faucette, Somerville, MA (US);
Matthew Pecukonis, Salem, MA (US);
Todd C. Zion, Marblehead, MA (US);
Thomas M. Lancaster, Stoneham, MA (US);
Wenyi Cai, Somerville, MA (US);
Ryan Faucette, Somerville, MA (US);
Matthew Pecukonis, Salem, MA (US);
Todd C. Zion, Marblehead, MA (US);
SmartCells, Inc., Berverly, MA (US);
Abstract
Methods for reducing the T-cell mitogenicity of lectin compositions are provided. In one aspect this is achieved by chemically modifying mitogenic lectin compositions under optimized conditions. Additionally or alternatively, the reduction in T-cell mitogenicity is achieved by removing unmodified subunits chemically modified mixtures. Modified lectin compositions with reduced T-cell mitogenicity are also provided as are uses of the inventive compositions.