The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 2010

Filed:

Dec. 19, 2007
Applicants:

Steven Bellon, Wellesley, MA (US);

Shon Booker, Thousand Oaks, CA (US);

Noel D'angelo, Thousand Oaks, CA (US);

Ingrid M. Fellows, Fresno, CA (US);

Jean-christophe Harmange, Andover, MA (US);

Tae-seong Kim, Thousand Oaks, CA (US);

Matthew Lee, Calabasas, CA (US);

Longbin Liu, Fresno, CA (US);

Mark H. Norman, Thousand Oaks, CA (US);

Inventors:

Steven Bellon, Wellesley, MA (US);

Shon Booker, Thousand Oaks, CA (US);

Noel D'Angelo, Thousand Oaks, CA (US);

Ingrid M. Fellows, Fresno, CA (US);

Jean-Christophe Harmange, Andover, MA (US);

Tae-Seong Kim, Thousand Oaks, CA (US);

Matthew Lee, Calabasas, CA (US);

Longbin Liu, Fresno, CA (US);

Mark H. Norman, Thousand Oaks, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

Selected pyridine and pyrimidine compounds of Formula I are effective for prophylaxis and treatment of diseases, such as c-met mediated diseases and/or HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.


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