The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 2010

Filed:

Jul. 25, 2007
Applicants:

Percy H. Carter, Princeton, NJ (US);

Robert J. Cherney, Newtown, PA (US);

John Hynes, Washington Crossing, PA (US);

Soo S. Ko, Hockessin, DE (US);

Anurag S. Srivastava, Belle Mead, NJ (US);

Zili Xiao, West Windsor, NJ (US);

Michael G. Yang, Narbeth, PA (US);

Inventors:

Percy H. Carter, Princeton, NJ (US);

Robert J. Cherney, Newtown, PA (US);

John Hynes, Washington Crossing, PA (US);

Soo S. Ko, Hockessin, DE (US);

Anurag S. Srivastava, Belle Mead, NJ (US);

Zili Xiao, West Windsor, NJ (US);

Michael G. Yang, Narbeth, PA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); C07D 401/12 (2006.01); A61K 31/501 (2006.01); A61K 31/5025 (2006.01); A61K 31/519 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 419/12 (2006.01); C07D 239/36 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates generally to modulators of chemokine receptor activity having unexpected combination of desirable pharmacological properties. Pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and prevention of inflammatory, allergic, autoimmune, metabolic, cancer and/or cardiovascular diseases, particularly diabetes, Crohn's disease, atherosclerosis, and multiple sclerosis, along with methods of preparing compounds and intermediates therefor. Metabolites of active compounds are also provided herein, pharmaceutical compositions and use thereof are also provided.


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