The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 30, 2010

Filed:

May. 24, 2007
Applicants:

Kaneyoshi Honjo, Takatsuki, JP;

Narito Tateishi, Mishima-gun, JP;

Nobuo Katsube, Mishima-gun, JP;

Inventors:

Kaneyoshi Honjo, Takatsuki, JP;

Narito Tateishi, Mishima-gun, JP;

Nobuo Katsube, Mishima-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/397 (2006.01); A61K 31/20 (2006.01); A61K 31/445 (2006.01); A61K 31/195 (2006.01); A61K 31/40 (2006.01);
U.S. Cl.
CPC ...
Abstract

A pharmaceutical composition for the treatment and/or prevention of cerebral ischemic diseases, which comprises two components, i.e. an astrocyte function-improving agent, preferably a compound represented by the formula (I): (wherein Ris hydroxy, etc., (1) n is 1, Ris hydrogen and Ris (alkyl of which one carbon atom is substituted by fluorine)-CH— or (2) n is 0 or 1, Ris hydrogen, etc., and Ris alkyl, etc.) and a thrombolytic agent, preferably tissue plasminogen activator, as active ingredients. The pharmaceutical composition of the present invention exhibits a synergistic therapeutic effect compared to independent administration of an astrocyte function-improving agent and a thrombolytic agent.


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