The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 30, 2010
Filed:
Mar. 17, 2004
Firelli Alonso-caplen, Tappan, NY (US);
Mark Cutler, Bloomingdale, NJ (US);
Mirelli Fino, Stamford, CT (US);
Earl Pursell, Valley Cottage, NY (US);
Robert Repetto, Garrison, NY (US);
Firelli Alonso-Caplen, Tappan, NY (US);
Mark Cutler, Bloomingdale, NJ (US);
Mirelli Fino, Stamford, CT (US);
Earl Pursell, Valley Cottage, NY (US);
Robert Repetto, Garrison, NY (US);
Wyeth Holdings Corporation, Madison, NJ (US);
Abstract
A process for producing isolated and purified respiratory syncytial virus (RSV) fusion (F) and attachment (G) glycoproteins in eukaryotic cell cultures infected with RSV cold-passaged, temperature-sensitive mutant subgroup A2 strain cpts-248/404 results in at least a 5-fold increase in F and G protein yields when compared with the parent A2 strain. Immunogenic compositions comprising the F and/or G protein(s) produced by this process can be formulated for in vivo administration to a host to confer protection against disease caused by RSV.