The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 2010
Filed:
Aug. 24, 2005
Applicants:
Daniella Gutman, Rishon Lezion, IL;
Lea Shachal, Ahuzat Barak, IL;
Inventors:
Daniella Gutman, Rishon Lezion, IL;
Lea Shachal, Ahuzat Barak, IL;
Assignee:
Taro Pharmaceutical Industries Limited, Haifa Bay, IL;
Primary Examiner:
Int. Cl.
CPC ...
C07H 17/08 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides a process of preparing a crystalline azithromycin monohydrate. The process involves dissolving azithromycin in a solution containing ethanol, adding the dissolved azithromycin into water to precipitate the crystals, isolating and drying the precipitate to a water content of about 5% (w/w) to about 7% (w/w). The resulting azithromycin monohydrate is stable, exhibiting less than 2% degradation, and non-hydroscopic.