The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 2010
Filed:
Mar. 29, 2007
Juergen Siekmann, Vienna, AT;
Katalin Varadi, Vienna, AT;
Herbert Gritsch, Vienna, AT;
Peter Turecek, Klosterneuburg, AT;
Juergen Siekmann, Vienna, AT;
Katalin Varadi, Vienna, AT;
Herbert Gritsch, Vienna, AT;
Peter Turecek, Klosterneuburg, AT;
Baxter International Inc., Deerfield, IL (US);
Baxter Healthcare, Wallisellen, CH;
Abstract
The invention is a proteinaceous construct comprising a Factor VIII molecule having at least a portion of the B domain intact, which is conjugated to a water-soluble polymer such as polyethylene glycol having a molecular weight of greater than 10,000 Daltons. The construct has a biological activity of at least 80% of the biological activity of native Factor VIII, and the in vivo half-life of the construct is increased by at least 1.5 fold as compared to the in vivo half-life of native factor FVIII.