The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 23, 2010

Filed:

Jun. 23, 2006
Applicants:

Jinlong Jiang, Scotch Plains, NJ (US);

Robert J. Devita, Westfield, NJ (US);

Sanjeev Kumar, Monroe, NJ (US);

Sander G. Mills, Scotch Plains, NJ (US);

Richard A. Tschirret-guth, Lawrenceville, NJ (US);

Inventors:

Jinlong Jiang, Scotch Plains, NJ (US);

Robert J. DeVita, Westfield, NJ (US);

Sanjeev Kumar, Monroe, NJ (US);

Sander G. Mills, Scotch Plains, NJ (US);

Richard A. Tschirret-Guth, Lawrenceville, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/4035 (2006.01); A61K 31/4439 (2006.01); C07D 209/46 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to certain hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.


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