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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7678802 B1

PDFFull Text
Date of Patent:
Mar. 16, 2010

Filed:

Mar. 03, 2004

Quinazolines useful as modulators of ion channels

Applicants:

Jesus E. Gonzalez, Iii, San Diego, CA (US);

Dean Mitchell Wilson, San Diego, CA (US);

Andreas Peter Termin, Encinitas, CA (US);

Peter Diederik Jan Grootenhuis, San Diego, CA (US);

Yulian Zhang, San Diego, CA (US);

Benjamin John Petzoldt, La Jolla, CA (US);

Lev Tyler Dewey Fanning, San Diego, CA (US);

Timothy Donald Neubert, San Diego, CA (US);

Roger Tung, San Diego, CA (US);

Esther Martinborough, San Diego, CA (US);

Nicole Zimmerman, San Diego, CA (US);

Inventors:

Jesus E. Gonzalez, III, San Diego, CA (US);

Dean Mitchell Wilson, San Diego, CA (US);

Andreas Peter Termin, Encinitas, CA (US);

Peter Diederik Jan Grootenhuis, San Diego, CA (US);

Yulian Zhang, San Diego, CA (US);

Benjamin John Petzoldt, La Jolla, CA (US);

Lev Tyler Dewey Fanning, San Diego, CA (US);

Timothy Donald Neubert, San Diego, CA (US);

Roger Tung, San Diego, CA (US);

Esther Martinborough, San Diego, CA (US);

Nicole Zimmerman, San Diego, CA (US);

Assignee:

Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);

Attorney:

Michael C. Badia

Primary Examiner:

Venkataraman Balasubramanian

Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); A61K 31/517 (2006.01); C07D 417/04 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 409/04 (2006.01); C07D 405/12 (2006.01); C07D 413/12 (2006.01); A61K 31/5377 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.

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