The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2010
Filed:
Oct. 09, 2008
Applicants:
James H. Werner, Los Alamos, NM (US);
Peter M. Goodwin, Los Alamos, NM (US);
Andrew P. Shreve, Santa Fe, NM (US);
Inventors:
James H. Werner, Los Alamos, NM (US);
Peter M. Goodwin, Los Alamos, NM (US);
Andrew P. Shreve, Santa Fe, NM (US);
Assignee:
Los Alamos National Security, LLC, Los Alamos, NM (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
Abstract
An apparatus and method for enabling precise, 3-dimensional, photoactivation localization microscopy (PALM) using selective, two-photon activation of fluorophores in a single z-slice of a sample in cooperation with time-gated imaging for reducing the background radiation from other image planes to levels suitable for single-molecule detection and spatial location, are described.