The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 09, 2010

Filed:

Nov. 07, 2007
Applicants:

Junichi Kobayashi, Hotaka-machi, JP;

Tetsuya Nakamura, Matsumoto, JP;

Ritsu Suzuki, Toyoshina-machi, JP;

Hideyuki Muranaka, Toyoshina-machi, JP;

Tomonaga Ozawa, Matsumoto, JP;

Yuichiro Kai, Toyoshina-machi, JP;

Takehiro Ishikawa, Toyoshina-machi, JP;

Tatsuhiro Kondo, Matsumoto, JP;

Tetsuro Tamai, Misato-mura, JP;

Satoshi Akahane, Mtsumoto, JP;

Inventors:

Junichi Kobayashi, Hotaka-machi, JP;

Tetsuya Nakamura, Matsumoto, JP;

Ritsu Suzuki, Toyoshina-machi, JP;

Hideyuki Muranaka, Toyoshina-machi, JP;

Tomonaga Ozawa, Matsumoto, JP;

Yuichiro Kai, Toyoshina-machi, JP;

Takehiro Ishikawa, Toyoshina-machi, JP;

Tatsuhiro Kondo, Matsumoto, JP;

Tetsuro Tamai, Misato-mura, JP;

Satoshi Akahane, Mtsumoto, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 217/14 (2006.01); C07C 217/20 (2006.01); C07D 307/79 (2006.01); A61K 31/195 (2006.01); A61P 1/16 (2006.01); A61P 3/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein Rand Rare each hydrogen or lower alkyl; R, R, Rand Rare each hydrogen, halogen, lower alkyl or lower alkoxy; Rand Rare each hydrogen, halogen, lower alkyl, halo-lower alkyl, lower alkoxy, cycloalkyl, aryl, heteroaryl, cyano, a hydroxyl group, lower acyl, carboxy or the like; Ris —C(O)—R, -A-C(O)—R, —O-A-C(O)—Ror a tetrazol-5-yl group, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.


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