The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2010
Filed:
Sep. 16, 2004
Marcello Allegretti, I-67100 L'Aquila, IT;
Maria Candida Cesta, I-67100 L'Aquila, IT;
Giuseppe Nano, I-67100 L'Aquila, IT;
Riccardo Bertini, I-67100 L'Aquila, IT;
Cinzia Bizzarri, I-67100 L'Aquila, IT;
Francesco Colotta, I-67100 L'Aquila, IT;
Marcello Allegretti, I-67100 L'Aquila, IT;
Maria Candida Cesta, I-67100 L'Aquila, IT;
Giuseppe Nano, I-67100 L'Aquila, IT;
Riccardo Bertini, I-67100 L'Aquila, IT;
Cinzia Bizzarri, I-67100 L'Aquila, IT;
Francesco Colotta, I-67100 L'Aquila, IT;
Other;
Abstract
Amidines and derivatives thereof of formula (I) are described. The process for their preparation and pharmaceutical compositions thereof are also described. The amidines of the invention are useful in the inhibition of chemotaxis of neutrophils induced by IL-8. The compounds of the invention are used in the treatement of psoriasis, ulcerative colitis, melanoma, chronic obstructive pulmonary disease (COPD), bullous pemphigo, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and in the prevention and treatment of damages caused by ischemia and reperfusion.