The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2010
Filed:
Mar. 11, 2004
Yingfu LI, Hamden, CT (US);
Kevin Bacon, San Diego, CA (US);
Hiromi Sugimoto, Aichi, JP;
Keiko Fukushima, Saitama, JP;
Kentaro Hashimoto, Wuppertal, DE;
Makiko Marumo, Nara-ken, JP;
Toshiya Moriwaki, Nara-ken, JP;
Noriko Nunami, Hyogo-ken, JP;
Naoki Tsuno, Osaka, JP;
Klaus Urbahns, Lund, SE;
Nagahiro Yoshida, Kyoto, JP;
Yingfu Li, Hamden, CT (US);
Kevin Bacon, San Diego, CA (US);
Hiromi Sugimoto, Aichi, JP;
Keiko Fukushima, Saitama, JP;
Kentaro Hashimoto, Wuppertal, DE;
Makiko Marumo, Nara-ken, JP;
Toshiya Moriwaki, Nara-ken, JP;
Noriko Nunami, Hyogo-ken, JP;
Naoki Tsuno, Osaka, JP;
Klaus Urbahns, Lund, SE;
Nagahiro Yoshida, Kyoto, JP;
Axikin Pharmaceuticals, Inc., San Diego, CA (US);
Abstract
The present invention relates to a benzenesulfonamide derivative of formula (I), which is useful as an active ingredient of pharmaceutical preparations. The benzenesulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders. In said formula, X represents O or S; Rrepresents formulae (a), (b), (c), (d), (e), (f), (g), (h), (i) or (j), the other substituents are as defined in claim