The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2010
Filed:
Sep. 11, 2003
Benjamin L. Viglianti, Durham, NC (US);
Mark W. Dewhirst, Durham, NC (US);
James R. Macfall, Graham, NC (US);
Zeljko Vujaskovic, Chapel Hill, NC (US);
Benjamin L. Viglianti, Durham, NC (US);
Mark W. Dewhirst, Durham, NC (US);
James R. MacFall, Graham, NC (US);
Zeljko Vujaskovic, Chapel Hill, NC (US);
Duke University, Durham, NC (US);
Abstract
Methods and compositions useful for detecting an in vivo blood pool, monitoring the distribution of a compound of interest to a desired site in an organism by magnetic resonance imaging, monitoring the accumulation of a compound of interest at a desired site in vivo by magnetic resonance imaging, and monitoring the release of liposomal contents to an external stimulus at a desired site in vivo by magnetic resonance imaging are disclosed. Some compositions comprise envirosensitive or non-sensitive liposomes. Contrast agents, such as manganese-based compounds, are also disclosed.