The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2010

Filed:

Oct. 02, 2007
Applicants:

An Thien VU, Pottstown, PA (US);

Stephen Todd Cohn, Spring, TX (US);

Eugene Anthony Terefenko, Center Valley, PA (US);

William Jay Moore, Collegeville, PA (US);

Puwen Zhang, Audubon, PA (US);

Paige Erin Mahaney, Pottstown, PA (US);

Eugene John Trybulski, Huntingdon Valley, PA (US);

Inventors:

An Thien Vu, Pottstown, PA (US);

Stephen Todd Cohn, Spring, TX (US);

Eugene Anthony Terefenko, Center Valley, PA (US);

William Jay Moore, Collegeville, PA (US);

Puwen Zhang, Audubon, PA (US);

Paige Erin Mahaney, Pottstown, PA (US);

Eugene John Trybulski, Huntingdon Valley, PA (US);

Assignee:

Wyeth LLC, Madison, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 215/00 (2006.01); A01N 33/02 (2006.01); A61K 31/135 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to arylamino-arylpropanolamine derivatives of formula I: or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromyalgia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof.


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