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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7671199 B1

PDFFull Text
Date of Patent:
Mar. 02, 2010

Filed:

Apr. 20, 2007

Process for the preparation of [(1r), 2s]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-5-methylpyrrolo[2, 1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester

Applicants:

Gerard A. Crispino, Lawrenceville, NJ (US);

Mourad Hamedi, Eatontown, NJ (US);

Thomas L. Laporte, Kendall Park, NJ (US);

John E. Thornton, Newtown, PA (US);

Jaan A. Pesti, Yardley, PA (US);

Zhongmin Xu, Princeton, NJ (US);

Paul C. Lobben, Lawrenceville, NJ (US);

David K. Leahy, Hightstown, NJ (US);

Jale Muslehiddinoglu, Hightstown, NJ (US);

Chiajen Lai, Kendall Park, NJ (US);

Lori Ann Spangler, Churchville, PA (US);

Robert P. Discordia, Pennington, NJ (US);

Francis S. Gibson, Pennington, NJ (US);

Inventors:

Gerard A. Crispino, Lawrenceville, NJ (US);

Mourad Hamedi, Eatontown, NJ (US);

Thomas L. LaPorte, Kendall Park, NJ (US);

John E. Thornton, Newtown, PA (US);

Jaan A. Pesti, Yardley, PA (US);

Zhongmin Xu, Princeton, NJ (US);

Paul C. Lobben, Lawrenceville, NJ (US);

David K. Leahy, Hightstown, NJ (US);

Jale Muslehiddinoglu, Hightstown, NJ (US);

Chiajen Lai, Kendall Park, NJ (US);

Lori Ann Spangler, Churchville, PA (US);

Robert P. Discordia, Pennington, NJ (US);

Francis S. Gibson, Pennington, NJ (US);

Assignee:

Britsol-Myers Squibb Company, Princeton, NJ (US);

Attorney:

Elliott Korsen

Primary Examiner:

Venkataraman Balasubramanian

Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/53 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to an improved process for preparing [(1R), 2S]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester of the formula: Compound I has been shown to be useful for the treatment of certain types of cancer.

Find Patent Forward Citations

Crispino, Gerard. (2010). Process for the preparation of [(1r), 2s]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-5-methylpyrrolo[2, 1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester (U.S. Patent No. 7671199). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7671199

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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