The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2010

Filed:

May. 13, 2005
Applicants:

Joseph L. Duffy, Cranford, NJ (US);

David E. Kaelin, Jr., East Brunswick, NJ (US);

Ann E. Weber, Scotch Plains, NJ (US);

Brian a Kirk, Sudbury, MA (US);

Inventors:

Joseph L. Duffy, Cranford, NJ (US);

David E. Kaelin, Jr., East Brunswick, NJ (US);

Ann E. Weber, Scotch Plains, NJ (US);

Brian A Kirk, Sudbury, MA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 31/41 (2006.01); A61K 31/42 (2006.01); A61K 31/415 (2006.01); A61K 31/40 (2006.01); C07D 401/10 (2006.01); C07D 271/06 (2006.01); C07D 263/24 (2006.01); C07D 249/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to novel cyclohexylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ('DP-IV inhibitors') and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.


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