The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2010

Filed:

Sep. 28, 2006
Applicants:

Timothy D. Machajewski, Emeryville, CA (US);

Cynthia M. Shafer, Emeryville, CA (US);

Christopher Mcbride, Emeryville, CA (US);

William Antonios-mccrea, Emeryville, CA (US);

Brandon M. Doughan, Emeryville, CA (US);

Barry H. Levine, Emeryville, CA (US);

Yi Xia, Emeryville, CA (US);

Maureen Mckenna, Emeryville, CA (US);

X. Michael Wang, Emeryville, CA (US);

Kris Mendenhall, Emeryville, CA (US);

Yasheen Zhou, Emeryville, CA (US);

Kristin Brinner, Emeryville, CA (US);

Zhenhai Gao, Emeryville, CA (US);

Daniel Poon, Emeryville, CA (US);

Paul Barsanti, Emeryville, CA (US);

Xiaodong Lin, Emeryville, CA (US);

Abran Costales, Emeryville, CA (US);

Alice Rico, Emeryville, CA (US);

Nathan Brammeier, Emeryville, CA (US);

Teresa Pick, Emeryville, CA (US);

Paul A. Renhowe, Emeryville, CA (US);

Inventors:

Timothy D. Machajewski, Emeryville, CA (US);

Cynthia M. Shafer, Emeryville, CA (US);

Christopher McBride, Emeryville, CA (US);

William Antonios-McCrea, Emeryville, CA (US);

Brandon M. Doughan, Emeryville, CA (US);

Barry H. Levine, Emeryville, CA (US);

Yi Xia, Emeryville, CA (US);

Maureen McKenna, Emeryville, CA (US);

X. Michael Wang, Emeryville, CA (US);

Kris Mendenhall, Emeryville, CA (US);

Yasheen Zhou, Emeryville, CA (US);

Kristin Brinner, Emeryville, CA (US);

Zhenhai Gao, Emeryville, CA (US);

Daniel Poon, Emeryville, CA (US);

Paul Barsanti, Emeryville, CA (US);

Xiaodong Lin, Emeryville, CA (US);

Abran Costales, Emeryville, CA (US);

Alice Rico, Emeryville, CA (US);

Nathan Brammeier, Emeryville, CA (US);

Teresa Pick, Emeryville, CA (US);

Paul A. Renhowe, Emeryville, CA (US);

Assignee:

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/5355 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 413/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, their stereoisomers, tautomers, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent. Disclosed also are methods of using the 2-amino-7,8-dihydro-6H-pyrido[4,3-d]pyrimidin-5-one compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative, viral, autoimmune, cardiovascular, and central nervous system diseases.


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