The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2010
Filed:
Nov. 07, 2001
Christophe Cazaux, Plaisance du Touch, FR;
Jean Sébastien Hoffmann, Toulouse, FR;
Thierry Louat, Saint Chamond, FR;
Laurence Servant, Toulouse, FR;
Khalil Bouayadi, Toulouse, FR;
Hakim Kharrat, Pechbusque, FR;
Christophe Cazaux, Plaisance du Touch, FR;
Jean Sébastien Hoffmann, Toulouse, FR;
Thierry Louat, Saint Chamond, FR;
Laurence Servant, Toulouse, FR;
Khalil Bouayadi, Toulouse, FR;
Hakim Kharrat, Pechbusque, FR;
Millegen, Labege, FR;
Abstract
The invention concerns a method for random mutagenesis comprising the replication of a DNA sequence in the presence of an efficient amount of at least a mutase, for example a Pol β, the random mutagenesis rate being at least of the order of 1 mutation for 400 base pairs. The replication product, optionally recombined and amplified, is cloned in an expression vector so as to generate mutated polypeptides which will be selected on the basis of the desired property or properties.