The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2010
Filed:
Nov. 27, 2006
Valery A. Petrenko, Auburn, AL (US);
Vitaly J. Vodyanoy, Auburn, AL (US);
Jennifer Cannon Sykora, Tallahassee, AL (US);
Valery A. Petrenko, Auburn, AL (US);
Vitaly J. Vodyanoy, Auburn, AL (US);
Jennifer Cannon Sykora, Tallahassee, AL (US);
Auburn University, Auburn, AL (US);
Abstract
Methods and compositions for identifying and characterizing the affinity of one or more ligands of a peptide are provided. In particular, a 'stripped phage ligand sensor device' (SPLSD) is provided comprising a sensor coupled to a binding element of interest. Binding elements of the invention comprise phage which in most embodiments express a peptide of interest on the phage surface. Assays using the SPLSD allow detection and quantitation of ligands. Also provided are improved methods for forming monolayers using phage. In particular, methods for the formation of monolayers using 'stripped phage' are provided. Further provided are monolayers and Langmuir-Blodgett films formed by the methods of the invention as well as substrates having deposited thereon the films of the invention. The monolayers, films and substrates of the invention are useful as components of biosensors and/or chemosensors.