The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 02, 2010
Filed:
Jun. 13, 2006
Nanao Horiishi, Yokohama, JP;
Toshiyuki Hakata, Hiroshima, JP;
Hirofumi Kawasaki, Hiroshima-ken, JP;
Shinji Uemoto, Hiroshima, JP;
Hiromitsu Misawa, Hiroshima, JP;
Seiichi Takahashi, Tokyo, JP;
Nanao Horiishi, Yokohama, JP;
Toshiyuki Hakata, Hiroshima, JP;
Hirofumi Kawasaki, Hiroshima-ken, JP;
Shinji Uemoto, Hiroshima, JP;
Hiromitsu Misawa, Hiroshima, JP;
Seiichi Takahashi, Tokyo, JP;
Toda Kogyo Corporation, Hiroshima-shi, Hiroshima-ken, JP;
Abstract
There are provided a pharmaceutical raw material capable of exhibiting a uniform functionality and producing magnetic particle-containing drugs for diagnosis and medical treatments with a high reproducibility. The pharmaceutical raw material comprises a monodisperse colloid sterile aqueous solution of magnetic iron oxide fine particles having an average particle diameter of 5 to 30 nm, a saturation magnetization of 50 to 90 Am/kg and a coercive force of 0.1 to 1.6 kA/m. The pharmaceutical raw material can be produced by forming magnetic iron oxide fine particles in the form of a colloid aqueous solution, purifying the resultant colloid aqueous solution of superparamagnetic iron oxide particles by water-washing and removing water-soluble salts by-produced upon the reaction from the reaction solution by an ordinary method, and replacing a dispersing medium of the purified colloid aqueous solution with ultrapure water.