The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2010

Filed:

Mar. 29, 2004
Applicants:

Paul Simmons, Kew, AU;

Andrew Zannettino, Highbury, AU;

Stan Gronthos, Colonial Light Gardens, AU;

Inventors:

Paul Simmons, Kew, AU;

Andrew Zannettino, Highbury, AU;

Stan Gronthos, Colonial Light Gardens, AU;

Assignee:

Angioblast Systems, Inc., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/26 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of enriching mesenchymal precursor cells including the step of enriching for cells based on at least two markers. The markers may be either i) the presence of markers specific for mesenchymal precursor cells, ii) the absence of markers specific for differentiated mesenchymal cells, or iii) expression levels of markers specific for mesenchymal precursor cells. The method may include a first solid phase sorting step utilizing MACS recognizing expression of the antigen to the STRO-1 Mab, followed by a second sorting step utilizing two colour FACS to screen for the presence of high level STRO-1 antigen expression as well as the expression of VCAM-1.


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