The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 02, 2010

Filed:

Sep. 05, 2008
Applicants:

Mitsuo Honda, Tokyo, JP;

Kazuhiro Matsuo, Kanagawa, JP;

Masaru Kanekiyo, Tokyo, JP;

Duanthanorm Promkhatkaew, Muang Nonthaburi, TH;

Inventors:

Mitsuo Honda, Tokyo, JP;

Kazuhiro Matsuo, Kanagawa, JP;

Masaru Kanekiyo, Tokyo, JP;

Duanthanorm Promkhatkaew, Muang Nonthaburi, TH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

A recombinant BCG vaccine being transformed with an expression vector that has a polynucleotide encoding a foreign antigenic protein, wherein the polynucleotide is a modified one in which the third position of each codon is substituted with G or C without a change of an amino acid. This recombinant BCG vaccine has an excellent expression rate of antigenic protein and, as a result, capable of inducing a sufficient immune response against target infectious disease, cancer, or the like at the same dose as that of the typical BCG vaccine.


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