The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2010

Filed:

Aug. 12, 2005
Applicants:

Tomomi Kosugi, Tokyo, JP;

Minoru Imai, Tokyo, JP;

Hiroaki Makino, Tokyo, JP;

Mika Takakuwa, Tokyo, JP;

Gen Unoki, Tokyo, JP;

Kenichiro Kataoka, Tokyo, JP;

Dale Robert Mitchell, Essex, GB;

Donald James Simpson, Essex, GB;

Clifford John Harris, Essex, GB;

Joelle Le, Essex, GB;

Yuko Yamakoshi, Tokyo, JP;

Inventors:

Tomomi Kosugi, Tokyo, JP;

Minoru Imai, Tokyo, JP;

Hiroaki Makino, Tokyo, JP;

Mika Takakuwa, Tokyo, JP;

Gen Unoki, Tokyo, JP;

Kenichiro Kataoka, Tokyo, JP;

Dale Robert Mitchell, Essex, GB;

Donald James Simpson, Essex, GB;

Clifford John Harris, Essex, GB;

Joelle Le, Essex, GB;

Yuko Yamakoshi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/04 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent MAPKAP-K2 inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for MAPKAP-K2 mediated disorder, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.


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