The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2010
Filed:
Sep. 01, 2006
Jay D. Keasling, Berkeley, CA (US);
Vincent J. J. Martin, Kensington, CA (US);
Douglas J. Pitera, Oakland, CA (US);
Seon-won Kim, Sacheon, KR;
Sydnor T. Withers, Iii, Richmond, CA (US);
Yasuo Yoshikuni, Berkeley, CA (US);
Jack D. Newman, Berkeley, CA (US);
Artem Valentinovich Khlebnikov, Mountain View, CA (US);
Jay D. Keasling, Berkeley, CA (US);
Vincent J. J. Martin, Kensington, CA (US);
Douglas J. Pitera, Oakland, CA (US);
Seon-Won Kim, Sacheon, KR;
Sydnor T. Withers, III, Richmond, CA (US);
Yasuo Yoshikuni, Berkeley, CA (US);
Jack D. Newman, Berkeley, CA (US);
Artem Valentinovich Khlebnikov, Mountain View, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl pyrophosphate. A related method comprises introducing into a host microorganism an intermediate in the mevalonate pathway and at least one heterologous nucleic acid sequence, each sequence coding for an enzyme in the mevalonate pathway necessary for converting the intermediate into isopentenyl pyrophosphate. The invention also provides nucleic acid sequences, enzymes, expression vectors, and transformed host cells for carrying out the methods.