The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2010

Filed:

Dec. 22, 2004
Applicants:

Shinji Yokoyama, Nagoya, JP;

Maki Tsujita, Nagoya, JP;

Reijiro Arakawa, Hamura, JP;

Tomoji Aotsuka, Hamura, JP;

Inventors:

Shinji Yokoyama, Nagoya, JP;

Maki Tsujita, Nagoya, JP;

Reijiro Arakawa, Hamura, JP;

Tomoji Aotsuka, Hamura, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/02 (2006.01); A61K 31/38 (2006.01); A01N 35/00 (2006.01); A61K 31/10 (2006.01); A01N 31/00 (2006.01); A01N 27/00 (2006.01); A61K 31/015 (2006.01);
U.S. Cl.
CPC ...
Abstract

To provide a pharmaceutically effective prophylactic/preventive agent for low-HDL cholesterolemia, focusing on an HDL-generating mechanism. The ABCA1 stabilizer of the present invention contains a bisphenol-type compound selected form probucol spiroquinone, probucol diphenoquinone, and probucol bisphenol as an effective ingredient. The ABCA1 stabilizer can continuously and stably express ABCA1 by a mechanism quite different from that of conventional processes, and thus is useful as prophylactic/preventive agent for low-HDL cholesterolemia or arteriosclerosis.


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