The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2010
Filed:
May. 29, 2006
Rolf Baenteli, Basel, CH;
Fraser Glickman, Basel, CH;
Jiri Kovarik, Zürich, CH;
Ian Lewis, Riehen, CH;
Markus Streiff, Birsfelden, CH;
Gebhard Thoma, Lörrach, DE;
Hans-günter Zerwes, Lörrach, DE;
Rolf Baenteli, Basel, CH;
Fraser Glickman, Basel, CH;
Jiri Kovarik, Zürich, CH;
Ian Lewis, Riehen, CH;
Markus Streiff, Birsfelden, CH;
Gebhard Thoma, Lörrach, DE;
Hans-Günter Zerwes, Lörrach, DE;
Novartis AG, Basel, CH;
Abstract
Disclosed are ergoline derivatives, Formula (I), wherein either each of Rand R, independently, is H; optionally Rand/or R-substituted-phenyl or -phenyl-Calkyl; optionally Rand/or R-substituted-heteroaryl or -heteroaryl-Calkyl; optionally Rand/or R-substituted heteroaryl N-oxide; optionally R-substituted C-Calkyl; optionally R-substituted C-Calkenyl, optionally R-substituted C-Calkynyl; optionally R-substituted C-Ccycloalkyl, or optionally R-substituted C-Ccycloalkenyl; or Rand Rform together with the nitrogen atom to which they are attached an optionally R-substituted 3-8 membered ring containing in addition to the nitrogen atom up to 2 heteroatoms selected independently from N, O and S; Ris H; OR; CHRR; (CH)NRR; CH—CH—OR; CH—CO—NRR; or CO—CHRR; Ris F; Cl; Br; I; OR; NRRor has one of the significances given for R; and Rhas one of the significances given for R, in free form or in salt form for preventing or treating disorders or diseases mediated by interactions between chemokine receptors and their ligands.