The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2010

Filed:

Dec. 17, 2008
Applicants:

Bruce A. Green, New City, NY (US);

Gary W. Zlotnick, New Windsor, NY (US);

Leah D. Fletcher, Geneseo, NY (US);

Arnold L. Smith, Mercer Island, WA (US);

Thomas J. Reilly, Columbia, MO (US);

Inventors:

Bruce A. Green, New City, NY (US);

Gary W. Zlotnick, New Windsor, NY (US);

Leah D. Fletcher, Geneseo, NY (US);

Arnold L. Smith, Mercer Island, WA (US);

Thomas J. Reilly, Columbia, MO (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

A P4 variant protein that has reduced enzymatic activity and that induces antibody to wild-type P4 protein and/or has good bactericidal activity against non-typable(NTHi) is useful as an active component in an immunogenic composition for humans. Methods of using these proteins, and compositions containing them in combination with additional antigens, are also provided.


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