The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2010
Filed:
Dec. 17, 2002
Applicants:
Ulrich Von Pawel-rammingen, Lund, SE;
Bjorn Johansson, Lund, SE;
Lars Björck, Lund, SE;
Inventors:
Assignee:
Hansa Medical Research AB, Lund, SE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); G01N 33/53 (2006.01); C07H 21/04 (2006.01); C07K 14/195 (2006.01); C12P 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
A polypeptide isolated fromis described, having IgG cysteine protease activity. The protease is designated IdeS, Immunoglobulin G-degrading enzyme of. A polypeptide comprises SEQ ID NO: 1 and variants and fragments thereof having IgG cysteine protease activity or the ability to generate an immune response againstin an individual. Polynucleotides encoding these polypeptides and the polypeptides may be used in generating an immune response in an individual. IdeS protease inhibitors may be used in the treatment ofinfection.