The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2010

Filed:

Oct. 16, 2006
Applicants:

William C. Olson, Ossining, NY (US);

Paul J. Maddon, Scarsdale, NY (US);

Naoya Tsurushita, Palo Alto, CA (US);

Paul R. Hinton, Sunnyvale, CA (US);

Maximillano Vasquez, Palo Alto, CA (US);

Inventors:

William C. Olson, Ossining, NY (US);

Paul J. Maddon, Scarsdale, NY (US);

Naoya Tsurushita, Palo Alto, CA (US);

Paul R. Hinton, Sunnyvale, CA (US);

Maximillano Vasquez, Palo Alto, CA (US);

Assignees:

Progenics Pharmaceuticals Inc., Tarrytown, NY (US);

Facet Biotech Corporation, Redwood, CT (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C12N 15/13 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention is directed an anti-CCR5 antibody which comprises (i) two light chains, each light chain comprising the expression product of a plasmid designated pVK:HuPRO14O-VK (ATCC Deposit Designation PTA-4097), and (ii) two heavy chains, each heavy chain comprising an expression product of either a plasmid designated pVgl:HuPRO140 HG2-VH (ATCC Deposit Designation PTA-4098) or a plasmic designated pVgl:HuPRO140 (mutB+D+I)-VH (ATCC Deposit Designation PTA-4099) or a fragment thereof which binds to CCR5 on the surface of a human cell.


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