The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2010
Filed:
Nov. 09, 2005
Tadanori Mayumi, Kobe-shi, Hyogo, JP;
Yasuo Tsutsumi, Toyono-gun, Osaka, JP;
Shinsaku Nakagawa, Yao-shi, Osaka, JP;
Madoka Taniai, Okayamai, JP;
Kakuji Torigoe, Okayamai, JP;
Masashi Kurimoto, Okayamai, JP;
Tadanori Mayumi, Kobe-shi, Hyogo, JP;
Yasuo Tsutsumi, Toyono-gun, Osaka, JP;
Shinsaku Nakagawa, Yao-shi, Osaka, JP;
Madoka Taniai, Okayamai, JP;
Kakuji Torigoe, Okayamai, JP;
Masashi Kurimoto, Okayamai, JP;
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama, JP;
Other;
Abstract
The present invention has objects to provide a mutant interferon-α protein having a higher anti-viral and anti-tumor activity and to provide an agent for susceptive diseases, which contains the mutant interferon-α protein as an effective ingredient; and solves the above objects by providing a mutant protein which has an amino acid sequence of human interferon-α subtype α8 represented by any one of SEQ ID NOs:1 to 3, where the arginine residue at the 145has been replaced with leucine, isoleucine, or valine residue; the alanine residue at the 146has been replaced with asparagine or serine residue; and the methionine residue at the 149has been replaced with tyrosine residue; and an agent for susceptive diseases, containing the mutant protein.