The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2010

Filed:

Oct. 05, 2007
Applicants:

Jeffrey Chisholm, Mountain View, CA (US);

Dmitry Koltun, Foster City, CA (US);

Jeff Zablocki, San Mateo, CA (US);

Eric Parkhill, San Francisco, CA (US);

Andrey Glushkov, Moscow, RU;

Natalya Vasilevich, Moscow, RU;

Timur Zilbershtein, Kazan, RU;

Andrew Cole, Robbinsville, NJ (US);

Tsung Lin, Princeton, NJ (US);

Ian Henderson, Hopewell, NJ (US);

Inventors:

Jeffrey Chisholm, Mountain View, CA (US);

Dmitry Koltun, Foster City, CA (US);

Jeff Zablocki, San Mateo, CA (US);

Eric Parkhill, San Francisco, CA (US);

Andrey Glushkov, Moscow, RU;

Natalya Vasilevich, Moscow, RU;

Timur Zilbershtein, Kazan, RU;

Andrew Cole, Robbinsville, NJ (US);

Tsung Lin, Princeton, NJ (US);

Ian Henderson, Hopewell, NJ (US);

Assignee:

Gilead Palo Alto, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 475/00 (2006.01); A61P 35/00 (2006.01); A61P 3/10 (2006.01); A61P 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I: The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.


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