The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2010

Filed:

Dec. 23, 2005
Applicants:

Niall Morrison Barr Martin, Cambridge, GB;

Graeme Cameron Smith, Cambridge, GB;

Stephen Philip Jackson, Cambridge, GB;

Vincent Junior M Loh, Horsham, GB;

Xiao-ling Fan Cockcroft, Horsham, GB;

Ian Timothy Williams Matthews, Horsham, GB;

Keith Allan Menear, Horsham, GB;

Frank Kerrigan, Cornwall, GB;

Alan Ashworth, London, GB;

Inventors:

Niall Morrison Barr Martin, Cambridge, GB;

Graeme Cameron Smith, Cambridge, GB;

Stephen Philip Jackson, Cambridge, GB;

Vincent Junior M Loh, Horsham, GB;

Xiao-Ling Fan Cockcroft, Horsham, GB;

Ian Timothy Williams Matthews, Horsham, GB;

Keith Allan Menear, Horsham, GB;

Frank Kerrigan, Cornwall, GB;

Alan Ashworth, London, GB;

Assignees:

Kudos Pharmaceuticals Limited, Cambridge, GB;

Maybridge Limited, Cornwall, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/60 (2006.01); C07D 221/02 (2006.01); C07D 237/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRor CRR; if X=NRthen n is 1 or 2 and if X=CRRthen n is 1; Ris selected from the group consisting of H, optionally substituted Calkyl, Caryl, Cheterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; Ris selected from H, hydroxy, amino; or Rand Rmay together form a spiro-Ccycloalkyl or heterocyclyl group; Rand Rare both hydrogen, or when X is CRR, R, R, Rand R, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and Ris selected from H and halo.


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