The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2010
Filed:
Aug. 04, 2004
Jared N. Cumming, Garwood, NJ (US);
Ulrich Iserloh, Hoboken, NJ (US);
Andrew Stamford, Chatham Township, NJ (US);
Corey Strickland, Martinsville, NJ (US);
Johannes H. Voigt, Union, NJ (US);
Yusheng Wu, New York, NY (US);
Ying Huang, East Brunswick, NJ (US);
Yan Xia, Edison, PA (US);
Samuel Chackalamannil, Califon, NJ (US);
Tao Guo, Dayton, NJ (US);
Douglas W. Hobbs, Yardley, PA (US);
Thuy X. H. Le, Monmouth Junction, NJ (US);
Jeffrey F. Lowrie, Pennington, NJ (US);
Kurt W. Saionz, Cranford, NJ (US);
Suresh D. Babu, Plainsboro, NJ (US);
Jared N. Cumming, Garwood, NJ (US);
Ulrich Iserloh, Hoboken, NJ (US);
Andrew Stamford, Chatham Township, NJ (US);
Corey Strickland, Martinsville, NJ (US);
Johannes H. Voigt, Union, NJ (US);
Yusheng Wu, New York, NY (US);
Ying Huang, East Brunswick, NJ (US);
Yan Xia, Edison, PA (US);
Samuel Chackalamannil, Califon, NJ (US);
Tao Guo, Dayton, NJ (US);
Douglas W. Hobbs, Yardley, PA (US);
Thuy X. H. Le, Monmouth Junction, NJ (US);
Jeffrey F. Lowrie, Pennington, NJ (US);
Kurt W. Saionz, Cranford, NJ (US);
Suresh D. Babu, Plainsboro, NJ (US);
Schering Corporation, Kenilworth, NJ (US);
Abstract
Disclosed are compounds of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein and the remaining variables are as defined in the specification. Also disclosed are pharmaceutical compositions comprising the compounds of formula I. Also disclosed are methods of treating cognitive or neurodegenerative diseases such as Alzheimer's disease. Also disclosed are pharmaceutical compositions and methods of treating cognitive or neurodegenerative diseases comprising the compounds of formula I in combination with a β-secretase inhibitor other than those of formula I, an HMG-CoA reductase inhibitor, a gamma-secretase inhibitor, a non-steroidal anti-inflammatory agent, an N-methyl-D-aspartate receptor antagonist, a cholinesterase inhibitor or an anti-amyloid antibody.