The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2010
Filed:
Aug. 30, 2002
Claude Rimington, Son, NO;
Greta Rimington, Legal Representative, Son, NO;
Kristian Berg, Heggedal, NO;
Diem Thuy Thi Tran, Oslo, NO;
Pal Kristian Selbo, Oslo, NO;
Claude Rimington, Son, NO;
Greta Rimington, legal representative, Son, NO;
Kristian Berg, Heggedal, NO;
Diem Thuy Thi Tran, Oslo, NO;
Pal Kristian Selbo, Oslo, NO;
Abstract
The present invention provides photosensitizing agents obtained by reducing a single double bond in the porphyrin macrocycle of a sulphonated meso-tetraphenylporphyrin, preferably a disulphonated meso-tetraphenylporphyrin such as TPPS. The resulting sulphonated meso-tetraphenyl chlorins include compounds of formula (I) (wherein X is —SOH; n, p, q and r are each independently 0 or 1; and the sum of n, p, q and r is an integer from 1 to 4, preferably at least 2, e.g. 2 or 4) isomers and isomer mixtures thereof. The compounds of the invention and their pharmaceutically acceptable salts find particular use as photosensitizing agents in the photochemical internalization of molecules and in photodynamic therapy.