The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2010
Filed:
Oct. 29, 2004
Takahide Ohishi, Ibaraki, JP;
Jun Takasaki, Ibaraki, JP;
Mitsuyuki Matsumoto, Ibaraki, JP;
Tetsu Saito, Ibaraki, JP;
Masazumi Kamohara, Ibaraki, JP;
Takatoshi Soga, Ibaraki, JP;
Takahide Ohishi, Ibaraki, JP;
Jun Takasaki, Ibaraki, JP;
Mitsuyuki Matsumoto, Ibaraki, JP;
Tetsu Saito, Ibaraki, JP;
Masazumi Kamohara, Ibaraki, JP;
Takatoshi Soga, Ibaraki, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
The invention relates to a convenient screening tool for identifying an agent for treating diabetes. The screening tool is a G protein-coupled receptor, a variant of the G protein-coupled receptor, or a homolog of the G protein-coupled receptor, which promotes insulin secretion under a high glucose concentration by activation. The invention also relates to cells transformed with an expression vector comprising a polynucleotide encoding and expressing the screening tool. The invention provides a convenient screening method for identifying an agent for treating diabetes, pharmaceutical compositions comprising the agent, and a process for manufacturing the pharmaceutical composition.