The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2010

Filed:

Jan. 08, 2003
Applicant:

Lawrence Rosenberg, Montreal, CA;

Inventor:

Lawrence Rosenberg, Montreal, CA;

Assignee:

McGill University, Montreal, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 51/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Pancreatic acinar cells contribute to β-cell neogenesis. Hamsters administered pentadecapeptide of INGAP protein demonstrated a 2-fold increase in the number of extra-islet acinar-associated β-cell clusters resulting in a 2.8-fold increase in the overall extra-islet β cell mass as compared to controls. In mammals acinar-to-β-cell differentiation provides an alternate pathway to β-cell neogenesis; INGAP peptide plays a significant role in this process.


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