The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2010
Filed:
Oct. 27, 2000
Isabel D. C. Markl, San Francisco, CA (US);
Peter A. Jones, La Cañada, CA (US);
Yoshitaka Tomigahara, Osaka, JP;
Gangning Liang, Rowland Heights, CA (US);
Hualin Fu, Los Angeles, CA (US);
Jonathan Cheng, Monterey Park, CA (US);
Isabel D. C. Markl, San Francisco, CA (US);
Peter A. Jones, La Cañada, CA (US);
Yoshitaka Tomigahara, Osaka, JP;
Gangning Liang, Rowland Heights, CA (US);
Hualin Fu, Los Angeles, CA (US);
Jonathan Cheng, Monterey Park, CA (US);
The University of Southern California, Los Angeles, CA (US);
Abstract
There is disclosed 103 novel methylation-altered DNA sequences ('marker sequences') that have distinct methylation patterns in cancer, compared to normal tissue. In many instances, these marker sequences represent novel sequences not found in the GenBank data base, and none of these marker sequences have previously been characterized with respect to their methylation pattern in human cancers including, but not limited to those of bladder and prostate. These 103 sequences have utility as diagnostic, prognostic and therapeutic markers in the treatment of human cancer, and as reagents in kits for detecting methylated CpG-containing nucleic acids.