The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2010

Filed:

Jun. 22, 2006
Applicants:

John R. Desjarlais, Pasadena, CA (US);

Paul Michael Steed, Chapel Hill, NC (US);

Jonathan Zalevsky, Riverside, CA (US);

David Edmund Szymkowski, Monrovia, CA (US);

David F. Carmichael, Monrovia, CA (US);

Inventors:

John R. Desjarlais, Pasadena, CA (US);

Paul Michael Steed, Chapel Hill, NC (US);

Jonathan Zalevsky, Riverside, CA (US);

David Edmund Szymkowski, Monrovia, CA (US);

David F. Carmichael, Monrovia, CA (US);

Assignee:

Xencor, Inc., Monrovia, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/19 (2006.01); A61K 38/00 (2006.01); C07K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to a pharmaceutical composition comprising a variant TNF-α protein that inhibits the activity of soluble TNF-α while substantially maintaining the activity of transmembrane TNF-α a buffer and a tonicity agent wherein said composition has a pH from approximately 5.0 to 8.0.


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