The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7662361 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 16, 2010

Filed:

Feb. 02, 2006
Applicants:

Jessie L.-s. AU, Columbus, OH (US);

M. Guillaume Wientjes, Columbus, OH (US);

Inventors:

Jessie L.-S. Au, Columbus, OH (US);

M. Guillaume Wientjes, Columbus, OH (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides methods and compositions for modulating the activity of therapeutic agents for the treatment of a cancer by administering one or more agents that (either alone or in combination) induces telomere damage and inhibits telomerase activity in the cancer cell. The method initially uses, e.g., a telomere damage-inducing agent such as paclitaxel, and a telomerase inhibitory agent such as AZT. The invention also provides methods for identifying other agents with telomere damage-inducing activity and/or telomerase inhibitory activity (as well as and compositions having such activity), for use in the treatment of cancer.


Find Patent Forward Citations

Au, Jessie L.-S.. (2010). Methods and compositions for modulating drug activity through telomere damage (U.S. Patent No. 7662361). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7662361

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