The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2010
Filed:
Nov. 17, 2000
Hajime Tei, Tokyo, JP;
Yoshiyuki Sakaki, Yokohama, JP;
Shin Yamazaki, Nashville, TN (US);
Michikazu Abe, Tokyo, JP;
Ri-ichi Takahashi, Tochigi, JP;
Hajime Tei, Tokyo, JP;
Yoshiyuki Sakaki, Yokohama, JP;
Shin Yamazaki, Nashville, TN (US);
Michikazu Abe, Tokyo, JP;
Ri-ichi Takahashi, Tochigi, JP;
University of Virginia, Madison Hall, Charlottesville, unknown;
Mitsubishi Pharma Corporation, Osaka, JP;
Abstract
The present invention relates to an isolated Period 1 (Per1) promoter DNA inducing rhythmical expression of a gene operably linked thereto. This invention also provides a DNA comprising a Period 1 promoter DNA and a gene operably linked thereto, the gene being under the regulation of the promoter DNA. The present invention further provides transformants and transgenic mammals into which the DNA has been introduced. The transformants and transgenic mammals are useful in the screening of pharmaceutical drugs against diseases and disorders pertaining to the circadian rhythm.