The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2010

Filed:

Apr. 12, 2007
Applicants:

Hans-joerg Buehring, Tuebingen, DE;

Sigrid Hojak, Berlin, DE;

Ingrid Albert, Tuebingen, DE;

Inventors:

Hans-Joerg Buehring, Tuebingen, DE;

Sigrid Hojak, Berlin, DE;

Ingrid Albert, Tuebingen, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/16 (2006.01); C12N 5/18 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); G01N 33/53 (2006.01); G01N 33/567 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a monoclonal antibody or fragment thereof, which binds specifically and/or selectively to human receptors of the Frizzled (FZD) family. It further relates to a hybridoma cell that produces the antibody according to the invention. Another object of the present invention is a method for the detection and/or isolation of receptors of the FZD family or homologs or fragments thereof in a biological sample and a method for the identification and/or isolation of biological material comprising or expressing receptors of the FZD family or homologs or fragments thereof. The invention further relates to the use of the antibody according to the invention or fragments thereof for the specific and/or selective detection and/or isolation of receptors of the FZD family, a composition comprising the monoclonal antibody according to the invention or fragments thereof, and a kit comprising the monoclonal antibody according to the invention or fragments thereof.


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