The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2010

Filed:

Oct. 24, 2006
Applicants:

Zeren Gao, Redmond, WA (US);

Charles E. Hart, Woodinville, WA (US);

Christopher S. Piddington, Thousand Oaks, CA (US);

Paul O. Sheppard, Granite Falls, WA (US);

Kimberly E. Shoemaker, Bellevue, WA (US);

Inventors:

Zeren Gao, Redmond, WA (US);

Charles E. Hart, Woodinville, WA (US);

Christopher S. Piddington, Thousand Oaks, CA (US);

Paul O. Sheppard, Granite Falls, WA (US);

Kimberly E. Shoemaker, Bellevue, WA (US);

Assignee:

ZymoGenetics, Inc., Seattle, WA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/08 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Polypeptide growth factor ZVEGF3, methods of making it, polynucleotides encoding it, antibodies that bind to it, and methods of using them are disclosed. The polypeptide comprises an amino acid segment that is at least 90% identical to residues 46-163 of SEQ ID NO:2 or residues 235-345 of SEQ ID NO:2. Multimers of the polypeptide are also disclosed. The polypeptide, multimeric proteins, and polynucleotides can be used in the study and regulation of cell and tissue development, as components of cell culture media, and as diagnostic agents. The antibodies may be used to inhibit cell growth.


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