The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2010
Filed:
Jul. 03, 2001
Applicants:
Martino Bolognesi, Torre d'Isola, IT;
Guido Grandi, Segrate, IT;
Inventors:
Martino Bolognesi, Torre d'Isola, IT;
Guido Grandi, Segrate, IT;
Assignee:
Novartis Vaccines and Diagnostics, S.R.L., Siena, IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G06F 19/00 (2006.01); A61K 39/12 (2006.01); C12N 7/00 (2006.01); G01N 33/566 (2006.01);
U.S. Cl.
CPC ...
Abstract
The extracellular loop of CD81 is a cellular receptor for the E2 protein of hepatitis C virus. A CD81 crystal structure has been elucidated and is provided for use in the structure-based design of compounds which bind to CD81 and thus block the binding of HCV. Methods such as docking and de novodrug design can be used.