The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2010

Filed:

Dec. 11, 2003
Applicants:

Joachim Schmitt, Hosbach, DE;

Gunter Boehm, Echzell, DE;

Bernd Stahl, Rosbach, DE;

Roland Schauer, Altenholz, DE;

Evelin Tiralongo, Neubrandenburg, DE;

Silke Schrader, Kiel, DE;

Inventors:

Joachim Schmitt, Hosbach, DE;

Gunter Boehm, Echzell, DE;

Bernd Stahl, Rosbach, DE;

Roland Schauer, Altenholz, DE;

Evelin Tiralongo, Neubrandenburg, DE;

Silke Schrader, Kiel, DE;

Assignee:

N.V. Nutricia, HM Zoetermeer H.M., NL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to novel enzymes, which transfer sialic acid from a donor molecule onto an acceptor molecule (trans-sialidases). The enzymes are isolated from the protozoan. The invention also relates to functional equivalents of said enzymes, to the nucleic acid sequences and amino acid sequences that code for the enzymes and their functional equivalents, to expression constructs and vectors that contain said sequences, to recombinant microorganisms that carry the inventive coding nucleic-acid sequences, to a method for the recombinant production of the inventive enzymes, to a method for isolating said enzyme from, to a method for the enzymatic sialization of acceptor molecules using the inventive enzymes, to effectors of the inventive trans-sialidases, to the use of the nucleic acid sequences, amino acid sequences, enzymes, effectors or sialization products for producing vaccines, medicaments, foodstuffs or food additives, in addition to the latter products obtained by the inventive method.


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