The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2010
Filed:
Aug. 24, 2007
Jeffrey Glenn, Palo Alto, CA (US);
Ella Sklan, Stanford, CA (US);
Kirk A. Staschke, Indianapolis, IN (US);
Tina Myers Oakes, Indianapolis, IN (US);
Jeffrey Glenn, Palo Alto, CA (US);
Ella Sklan, Stanford, CA (US);
Kirk A. Staschke, Indianapolis, IN (US);
Tina Myers Oakes, Indianapolis, IN (US);
The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);
Eli Lily and Company, Indianapolis, IN (US);
Abstract
The invention features methods and compositions for screening for agents that modulate replication of a virus, particularly Flaviviridae virus (particularly hepatitis C virus (HCV)), where the methods provide for detection of agents that modulate the binding of TBC and NS5A, the inhibition of TBC activity, inhibition of Rab1 activity, and/or the expression of the TBC protein and/or Rab1 protein. The invention also features methods of controlling viral replication, and agents useful in such methods.